OAS1 genotype linked to multiple sclerosis severity
نویسندگان
چکیده
منابع مشابه
OAS1 gene haplotype confers susceptibility to multiple sclerosis.
Multiple sclerosis (MS) is associated with genetic susceptibility and unknown environmental triggers, possible viral infections, but the specific etiological mechanism that subsequently develops into an inflammatory/autoimmune cascade of events is poorly understood. Recently, genetic variants of 2',5'- oligoadenylate synthetase 1 (OAS1) gene, a critical enzyme involved in innate antivirus respo...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2010
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2010.134